There are currently 49 active clinical trials seeking participants for Autism research studies. The states with the highest number of trials for Autism participants are California, Florida, Ohio and New York.
The Neurodevelopmental and Behavioral Phenotyping Screening Protocol
NCT00271622
Recruiting
The purpose of this protocol is to allow for the careful evaluation of healthy volunteers and individuals with risk for psychiatric disorders or neurodevelopmental disorders, such as autism spectrum disorder for specific protocols at NIH.
Gender:
ALL
Ages:
6 weeks and above
Trial Updated:
06/26/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurologic Disorders, Autism, Neurodegenerative Disease, Neurobehavioral Manifestation
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Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
NCT01778504
Recruiting
Background: - Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood. Researchers want to look at people of all ages who have these disorders that started in childhood. They will also look at relatives of people with these disorders. This information will allow doctors to learn more about childhood behavioral problems and how they are inherited. It may also help doct... Read More
Gender:
ALL
Ages:
99 years and below
Trial Updated:
06/26/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Neurological Disorder, Autism, Sleep
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Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
NCT03434080
Recruiting
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This ma... Read More
Gender:
ALL
Ages:
Between 3 months and 5 years
Trial Updated:
06/25/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Autism, Cerebral Palsy
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A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
NCT04031469
Recruiting
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
06/23/2025
Locations: Sabine Hazan, Ventura, California
Conditions: Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder, Autism Spectrum Disorder High-Functioning, Alzheimer Disease, Alzheimer Dementia (AD), Alzheimer Dementia, Alzheimer Disease (AD), Crohn, Crohn Colitis, Crohn Disease (CD), Crohn Disease Colon, Myalgic Encephalomyelitis, ME/CFS, Myalgic Encephalomyelitis (ME), Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Psoriasis, Psoriasis Annularis, Psoriasis Chronic, Chronic Urinary Tract Infection, Ulcerative Colitis (Disorder), Ulcerative Colitis (UC), Ulcerative Colitis Acute, Ulcerative Colitis Chronic, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive, Constipation Chronic Idiopathic, Constipation, Celiac, Celiac Disease, Celiac Sprue, Lyme Arthritis, Lyme Borreliosis, Nervous System, Lyme Disease, Chronic, Cholesterol, Cholesterol Level, High, Cancer, Colon Cancer, Amyotrophic Lateral Sclerosis (ALS), Amyotrophic Lateral Sclerosis, Rheumatoid Arthritis (RA), Rheumatoid Arthritis - Rheumatism, Chronic Fatigue Syndrome (CFS), PARKINSON DISEASE (Disorder), Parkinson Disease, Parkinson Disease (PD), Depression, Major Depressive Disorder (MDD), Depression Disorder, Depression in Adults, Anxiety, Anxiety Disorder Generalized, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Disorder OCD, Obsessive - Compulsive Disorder, Bipolar, Bipolar 1 Disorder, Bipolar Disorder (BD), Bipolar Disorder I and II, Bipolar and Related Disorders, Migraine, Migraine Disorder, Diabetes (DM), Diabetes, Lupus, Lupus Erythematosus, Epidermolysis Bullosa (EB), Mesothelioma, Mesothelioma Malignant, IBS (Irritable Bowel Syndrome), Irritable Bowel, IBS - Irritable Bowel Syndrome, Irritable Bowel Syndrome (IBS), Eczema, Eczema Atopic Dermatitis, Acne, Myasthaenia Gravis, Gout
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SenseToKnow Autism Screening Device Validation Study
NCT05874466
Recruiting
This is a pivotal, prospective, double-blind, study to evaluate the sensitivity and specificity of the SenseToKnow app for the detection of autism spectrum disorder in children 16-36 months of age.
Gender:
ALL
Ages:
Between 16 months and 36 months
Trial Updated:
05/23/2025
Locations: Duke University, Durham, North Carolina
Conditions: Autism, Autism Spectrum Disorder
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Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism
NCT06627205
Recruiting
The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD). Treatment will be delivered via secure telemedicine platform and consist of parent-training in delivering the intervention.
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
05/13/2025
Locations: Stanford University, Stanford, California
Conditions: Autism Spectrum Disorder (ASD), Autism
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Early Diagnostic Response Model (EDRM)
NCT05419895
Recruiting
Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this study is to develop, pilot, and evaluate a diagnostic protocol for children identified at high risk for autism in the BCW early intervention program screening (part of a public health service). This program evaluation will be using pre- and post-data and data collected thro... Read More
Gender:
ALL
Ages:
Between 16 months and 36 months
Trial Updated:
05/05/2025
Locations: Emory Autism Center, Atlanta, Georgia
Conditions: Autism Spectrum Disorder, Autism
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Project VOICES: Vocal Optimization in Children Elevating the Spectrum
NCT06875843
Recruiting
Thirty percent of children with autism barely talk or do not talk at all despite years of intervention. This study aims to address this important and long-standing challenge by developing a novel intervention to increase the quantity and quality of vocalizations (i.e., sounds children make before words) and expressive language in young children with autism (aged 2 to 5 years) with minimal verbal skills. The intervention includes contingent responses to the child's vocalizations and vocal elicita... Read More
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
05/01/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Autism
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Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
NCT06859918
Recruiting
The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings. The Investigators will... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/22/2025
Locations: Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Autism Spectrum Disorder, Autism, Autistic Disorder, Asperger Syndrome
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Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers
NCT05880225
Recruiting
The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and social communication skills, or a music-enhanced version of RIT. Throughout their participation in the intervention, toddlers will complete study procedures of viewing naturalistic videos of infant-dire... Read More
Gender:
ALL
Ages:
Between 18 months and 36 months
Trial Updated:
04/22/2025
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Autism, Autism Spectrum Disorder
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Family, Responsibility, Education, Support, and Health for Families With a Child With Autism
NCT05741840
Recruiting
The objective of this proposed study is to collect initial efficacy data on a telehealth parent-based behavioral program for children with autism and overweight or obesity (PBT-A), compared with health education (HE).
Gender:
ALL
Ages:
Between 6 years and 12 years
Trial Updated:
03/27/2025
Locations: UC San Diego Center for Healthy Eating and Activity Research (CHEAR), La Jolla, California
Conditions: Autism Spectrum Disorder, Obesity, Childhood, Autism
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Biomarkers Research in Anxiety for Validation and Efficacy
NCT06221176
Recruiting
A within-subjects design will be used for this preliminary investigation of four biomarkers across two contexts of use: prediction of treatment response (i.e., stratification) and quantification of response (i.e., change).
Gender:
ALL
Ages:
Between 3 years and 6 years
Trial Updated:
03/10/2025
Locations: Boston Children's Hospital, Two Brookline Place, Brookline, Massachusetts
Conditions: Autism, Autism Spectrum Disorder
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